The merger of Genentech and Roche brought together the premier developer of targeted therapeutics and clinical diagnostics. This unique partnership led to the development of the first Roche-wide PHC efforts or “Development of Drugs and Diagnostics Together”. To help realize the power of this partnership we developed goals for each molecule team to have a formal biomarker/diagnostic plan and to partner early with their Roche DIA colleagues to ensure both molecule and assay plan were aligned.